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Zyvox Warnings and Precautions
Taking Zyvox increases your risk of seizures, vision loss, and lactic acidosis -- as well as a potentially life-threatening reaction known as serotonin syndrome. Because of the risks involved with Zyvox, it's important to understand the warnings and precautions before starting treatment. Certain people should avoid the antibiotic entirely, including those who are taking a monoamine oxidase inhibitor (MAOI).
What Should I Tell My Healthcare Provider?
You should talk with your healthcare provider prior to taking Zyvox® (linezolid) if you have:- Kidney disease, such as kidney failure (renal failure)
- High blood pressure (hypertension) or a history of high blood pressure
- Bone marrow problems, such as leukemia, anemia, lymphoma, or recent chemotherapy
- Pheochromocytoma, a rare tumor of the adrenal gland
- Carcinoid syndrome (symptoms caused by carcinoid tumors, which are most often found in the gastrointestinal tract or the lungs)
- Untreated hyperthyroidism (overactive thyroid), inflammation of the thyroid gland, or high thyroid hormone levels in your blood
- Ever had a seizure
- Phenylketonuria (a problem with amino acids)
- Recently been treated with other antibiotics or are currently being treated for another infection with other antibiotics
- Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant
- Breastfeeding.
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medications, vitamins, and herbal supplements.
Written by/reviewed by: Susan Lakey, PharmD, MPH
Last reviewed by: Kristi Monson, PharmD