Zyvox Uses

Using Zyvox for Skin and Soft Tissue Infections

Skin infections commonly call for treatment with antibiotics. These infections can range from minor cuts and scrapes to severe, deep infections involving soft tissue. Soft tissues are tissues that connect, support, and surround other body organs, such as muscle, fat, tendons, and synovial tissue (tissue lining the joints).
Healthcare providers classify skin and soft tissue infections as either complicated or uncomplicated, based largely on how severe the infection is.
For example, complicated infections may:
  • Involve deep soft tissue (such as muscle and fat)
  • Require surgery for healing
  • Occur in people who have a disease that makes it difficult for the infection to heal (such as diabetes).
Simple abscesses or minor cellulitis are examples of uncomplicated skin infections. Severe cellulitis and diabetic foot infections are examples of complicated skin infections.
Zyvox can treat both uncomplicated and complicated skin and soft tissue infections caused by certain bacteria. Specifically, the drug can be used when the infection is caused by the following bacteria:
  • Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA)
  • Streptococcus pyogenes
  • Streptococcus agalactiae.

Using Zyvox for Vancomycin-Resistant Enterococcus Infections

Enterococci are bacteria that are normally found in the human intestines and the female genital tract. Although this type of bacteria is usually not harmful, it can sometimes cause infections. One of the antibiotics used to treat enterococci infections is called vancomycin (Vancocin®). Vancomycin-resistant enterococcus (VRE) is a term used to describe enterococcus that has become resistant to vancomycin treatment.
The majority of VRE infections occur in hospitals, where antibiotic resistance is more common and people are generally sicker. Some of the types of infections caused by VRE may include but are not limited to:
Some people may be more susceptible to VRE infections. Things that increase the risk for a VRE infection may include:
  • Long-term hospitalization, especially if antibiotics are needed in the hospital
  • Intensive care unit (ICU) hospital stay
  • Previous treatment with vancomycin (Vancocin) or other antibiotics for long periods
  • Certain medical conditions, such as advanced renal disease requiring dialysis, cancer, and organ transplant
  • Surgical procedures, such as abdominal (stomach) or chest surgery
  • Use of certain medical devices that stay in the body for long periods, such as urinary or IV catheters.
There are several different types of enterococci bacteria. Zyvox is used to treat VRE infections caused specifically by Enterococcus faecium.
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