Zyvox Drug Interactions

If you are taking Zyvox, be aware that this antibiotic can cause serious reactions with many other medications, such as Prozac, albuterol, methadone, and dopamine. Reactions are even possible after treatment ends, as the drug's effects continue for two weeks after stopping it. To reduce your risk of potentially life-threatening interactions with Zyvox, tell your healthcare provider about all of your current medications.

An Overview of Interactions With Zyvox

Zyvox® (linezolid) can potentially react with a number of other medications. Because there are so many Zyvox drug interactions that may be dangerous, it is important to check with your healthcare provider before taking any medications, whether prescription or over-the-counter (OTC), while you are taking Zyvox.
 
The effects of this medication may continue for two weeks after you stop taking it. Therefore, you may be at risk for drug interactions if you recently took Zyvox.
 
Some of the medicines that may lead to serious Zyvox drug interactions include but are not limited to:
 
  • Altretamine (Hexalen®)
  • Antidepressants, such as:
     
    • Miscellaneous antidepressants, such as:

 

 

    • Monoamine oxidase inhibitors (MAOIs), such as:
 
 
 
 
 
 
 
 
 
 
  • Pressors, such as:
     
    • Dopamine (Intropin®)
    • Dobutamine (Dobutrex®)
    • Epinephrine (Adrenalin®, EpiPen®)
    • Norepinephrine (Levophed®)
 
  
Zyvox Drug Interactions Article Continues on Next Page >
Written by/reviewed by: Susan Lakey, PharmD, MPH
Last reviewed by: Kristi Monson, PharmD
 
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