Zyvox Drug Interactions

Methyldopa
Taking methyldopa and Zyvox together may increase your risk of dangerous side effects, such as high blood pressure (hypertension). If you take these medications together, your healthcare provider will need to monitor you closely.
 
Narcotic Pain Medications
Taking Zyvox with narcotics can increase your chance of serious side effects, including low blood pressure (hypotension) or serotonin syndrome, a potentially life-threatening reaction. Talk to your healthcare provider before taking these medications together.
 
Pressors
Combining pressors and Zyvox may increase your risk of dangerous side effects, such as high blood pressure (hypertension). These medications should be used together with caution. If you must take these drugs together, your healthcare provider will need to monitor you closely.
 
Tramadol
Combining Zyvox with tramadol increases your risk of a dangerous and potentially life-threatening reaction called serotonin syndrome. If you take these medications together, your healthcare provider should monitor you closely for signs of this reaction (see Zyvox Warnings and Precautions).
 
Triptans
Combining Zyvox with a triptan medication may increase your risk of a dangerous and potentially life-threatening reaction called serotonin syndrome. If you take these medications together, your healthcare provider should monitor you closely for signs of this reaction (see Zyvox Warnings and Precautions for more information).
 
Tryptophan
Taking tryptophan and Zyvox together increases the risk of dangerous side effects, such as high blood pressure (hypertension), confusion, or agitation. Talk to your healthcare provider before combining these drugs.
 
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Zyvox Medication Information

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