Zyvox and Pregnancy

Although it hasn't been studied adequately in pregnant women, Zyvox (linezolid) has been studied in pregnant animals. In these studies, certain problems were reported, such as miscarriages and decreased fetal weight. It's important to note, however, that humans do not always respond to medicines that same way that animals do. This antibiotic may be prescribed during pregnancy if the benefits outweigh the risks.

Can Pregnant Women Take Zyvox?

Zyvox® (linezolid) is a prescription antibiotic used to treat serious infections. Studies in animals suggest the drug may not be safe for use during pregnancy, although the full risks are not currently known.
 

What Is Pregnancy Category C?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause harm to the fetus in animal studies.
 
In addition, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
 
When given to pregnant mice at doses high enough to cause problems in the mothers, Zyvox caused miscarriages and decreased fetal weight. When given in smaller doses to pregnant rats and rabbits, it caused reduced fetal weight in both animals and problems with bone development in rats. Zyvox did not cause any birth defects in mice, rats, or rabbits. It has not been adequately studied in pregnant humans.
 
However, it is important to note that animals do not always respond to medicines the same way that humans do. Therefore, a pregnancy Category C medicine may be given to a pregnant woman if the healthcare provider believes that the benefits to the woman outweigh any possible risks to the unborn child.
 
It is worth noting that Zyvox is usually reserved for only the most serious of infections; in many cases, the potentially life-saving benefits to the mother and therefore to the fetus probably outweigh the unknown risks.
 
Pregnancy and Pain

Zyvox Medication Information

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