Sudafed PE Uses

Sudafed PE is a medication that is used for the treatment of nasal congestion due to allergies or the common cold. This non-prescription medication can also help relieve sinus congestion and pressure. Sudafed PE is approved for use in children; the liquid is approved for use in children age 4 to 11, and the tablets are approved for children as young as 12 years old. Some possible off-label uses of Sudafed PE include treating fluid build-up in the ears and urinary incontinence.

What Is Sudafed PE Used For?

Sudafed PE® (phenylephrine hydrochloride) is a decongestant medication available without a prescription. Approved uses for Sudafed PE include relieving:
 
It should be noted that there are several different Sudafed PE medications, many of which contain additional active ingredients other than phenylephrine. This article focuses primarily on phenylephrine, not the other active ingredients in such products.
 

How Does Sudafed PE Work?

Sudafed PE is part of a class of drugs called decongestants. Specifically, it works by stimulating certain receptors known as alpha-adrenergic receptors. In the lining of the nose and sinuses, this action causes the blood vessels to constrict, allowing less fluid to leave the blood vessels and decreasing inflammation. This helps to relieve nasal and sinus congestion.
 

Can Children Use It?

Children's Sudafed PE Nasal Decongestant Liquid is approved for use in children age 4 to 11 years old. Sudafed PE Nasal Decongestant tablets are approved for use in children as young as 12 years old.
 
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Sudafed PE Drug Information

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