This medication was formulated in response to regulations that require original Sudafed (
pseudoephedrine) products to be kept "behind the counter" to avoid the misuse of the medication to make
methamphetamine. These regulations do not apply to Sudafed PE.
As a sinus and nasal decongestant, Sudafed PE works by stimulating certain receptors known as alpha-adrenergic receptors. In the lining of the nose and sinuses, this action causes the blood vessels to constrict, allowing less fluid to leave the blood vessels and decreasing inflammation. This helps to relieve nasal and sinus congestion.
Although most people tolerate this medication well, it is not suitable for everyone. Before starting treatment with Sudafed PE, make sure to talk to your healthcare provider about any other medical conditions you may have or any other medications you are taking (including vitamins and herbal supplements). Some of the common side effects include
insomnia, dizziness, and nervousness.
(Click Sudafed PE for a closer look at using this drug for allergies or the common cold. This article also explains what to tell your healthcare provider before using this drug, covers general dosing guidelines, and offers tips on when and how to use this medication.)
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