Drug Interactions With Pseudoephedrine

There are a number of medications that may cause pseudoephedrine drug interactions, including carbonic anhydrase inhibitors, sodium bicarbonate antacids, SNRI antidepressants, and monoamine oxidase inhibitors. Some of these drug interactions can increase your risk of serious problems (such as high blood pressure, an irregular heart rhythm, or seizures), while others can affect the drug levels in your blood.

Interactions With Pseudoephedrine: An Overview

Pseudoephedrine can potentially interact with a number of other medications. Some of the medicines that may lead to drug interactions with pseudoephedrine include (but are not limited to):



  • Carbonic anhydrase inhibitors, such as:


    • Acetazolamide (Diamox®)
    • Dichlorphenamide (Daranide®)
    • Methazolamide


  • Iobenguane I 123 (AdreView™)
  • Monoamine oxidase inhibitors (MAOIs), including:



  • Phenothiazine medications, including:





(It should be noted that many pseudoephedrine products also contain other active ingredients. This article focuses on the drug interactions for pseudoephedrine, not for the other active ingredients in such combination products.)
5 Tips to Keep a Cold at Bay

Pseudoephedrine Drug Information

Referring Pages:
Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2018 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.