Neo-Synephrine Warnings and Precautions

Before you start using Neo-Synephrine, warnings and precautions for the nasal spray should be fully understood. For example, Neo-Synephrine is not suitable for everyone. You may not be able to safely use it if you have certain medical conditions, such as glaucoma, diabetes, or heart disease. Precautions and warnings also apply to people with certain allergies and to women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider Before Taking Neo-Synephrine?

You should talk with your healthcare provider prior to using Neo-Synephrine® (phenylephrine or oxymetazoline nasal spray) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Neo-Synephrine Warnings and Precautions

Some warnings and precautions to be aware of prior to using Neo-Synephrine include the following:
  • Neo-Synephrine can cause problems in people with glaucoma, an enlarged prostate, diabetes, hyperthyroidism, uncontrolled high blood pressure, or heart disease. If you have one of these conditions, do not take this medication without first checking with your healthcare provider.
  • Neo-Synephrine could potentially interact with other medications (see Neo-Synephrine Drug Interactions).
  • Do not use Neo-Synephrine more than directed or for longer than three days at a time. Rebound congestion (a worsening of the congestion due to the medication) could occur (see Neo-Synephrine Addiction for more information).
  • Do not share the nasal spray with anyone else, as this could spread an infection.
  • Do not tip your head back when using Neo-Synephrine, as this increases the chance of it running down your throat, which may increase the absorption of the medication into the bloodstream and might increase the risk of Neo-Synephrine side effects.
  • Neo-Synephrine is considered a pregnancy Category C medication. This means that it might not be safe for use during pregnancy, although the full risks are not currently known (see Phenylephrine and Pregnancy or Oxymetazoline Nasal Spray and Pregnancy for more information).
  • It is unknown if Neo-Synephrine passes through breast milk. Therefore, if you are breastfeeding, make sure to talk with your healthcare provider before using this drug (see Phenylephrine and Breastfeeding or Oxymetazoline Nasal Spray and Breastfeeding for more information).
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