Neo-Synephrine Drug Interactions

Neo-Synephrine Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Neo-Synephrine is combined with any of the drugs listed above.
 
Cannabinoids
Taking Neo-Synephrine with a cannabinoid drug increases the risk of a rapid heart rate (tachycardia), which can be dangerous. If you notice a rapid heart rate while taking Neo-Synephrine (with or without a cannabinoid), it is probably best to stop taking it.
 
Iobenguane I 123
Neo-Synephrine may interfere with tests that use iobenguane I 123. You should not take Neo-Synephrine for several days before a laboratory test that involves iobenguane I 123 (your healthcare provider will give you more specific instructions).
 
Monoamine Oxidase Inhibitors (MAOIs)
If a significant amount of oxymetazoline or phenylephrine (the active ingredient in Neo-Synephrine) is absorbed into the bloodstream, it is possible that combining Neo-Synephrine and an MAOI could cause life-threatening problems. If you are on an MAOI, make sure to check with your healthcare provider before using Neo-Synephrine. Often, it is recommended to avoid Neo-Synephrine while taking an MAOI or even within 14 days of taking an MAOI.
 
Tricyclic Antidepressants
Tricyclic antidepressants could increase the risk of high blood pressure due to Neo-Synephrine. This is most likely to happen if a significant amount of Neo-Synephrine is absorbed into the bloodstream, which might occur if the spray runs down the back of the throat and is swallowed. If you take a tricyclic antidepressant, check with your healthcare provider before taking Neo-Synephrine.
 

Final Thoughts on Drug Interactions With Neo-Synephrine

It is possible that not all Neo-Synephrine drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
 
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Neo-Synephrine Drug Information

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