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Your dosage of Sudafed PE will depend on several factors, such as your age, other medical conditions you may have, and other medications you are taking. For adults and children at least 12 years old, the recommended dosage is one tablet every four hours, not to exceed six tablets in 24 hours. There is also a Sudafed PE liquid available for children as young as 4 years old.

Sudafed PE Dosage: An Introduction

The recommended dose of Sudafed PE® (phenylephrine hydrochloride) will vary, depending on a number of factors, including:
  • The particular product
  • Your age
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically instructs you to do so.
(It should be noted that there are several different Sudafed PE medications, many of which contain additional active ingredients other than phenylephrine. This article focuses primarily on the single ingredient phenylephrine, not the products with other active ingredients.)

Sudafed PE Dosing for Adults and Older Children

The recommended dosage for immediate-release Sudafed PE tablets in adults and children age 12 years old and older is one tablet (10 mg) every four hours, not to exceed six tablets in 24 hours.

Sudafed PE Dosing for Young Children

For Sudafed PE Nasal Decongestant Liquid, the recommended dose for children age 6 to 11 years old is two teaspoonfuls (10 mL, 5 mg) every four hours, not to exceed six doses in 24 hours. For children age 4 to 5 years old, the recommended dose is one teaspoonful (5 mL, 2.5 mg) every four hours, not to exceed six doses in 24 hours. Do not use in children younger than four years old.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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