Cold Home > Precautions and Warnings With Diphenhydramine

Who Should Not Take Diphenhydramine?

According to the manufacturer of diphenhydramine, you should not take diphenhydramine if you are:
  • Allergic to diphenhydramine or any inactive components used to make diphenhydramine products. Your healthcare provider or pharmacist has a list of the inactive ingredients.
  • Breastfeeding (see Diphenhydramine and Breastfeeding), although some sources consider diphenhydramine to be compatible with breastfeeding.
Additionally, diphenhydramine should never be used in newborns or premature infants.

Final Thoughts

There are a number of situations in which diphenhydramine should not be taken, as well as several precautions and warnings people should be aware of before starting the medication. However, it is possible that not all of the warnings were discussed in this article. Therefore, talk with your healthcare provider about the specific diphenhydramine warnings and precautions that may apply to you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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