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Chlorpheniramine is a form of antihistamine often used for treating allergies, the common cold, and hives. It works by blocking H1 receptors and acetylcholine receptors in the body. The medication comes in several different forms, including tablets, capsules, and a liquid, and is taken by mouth every 4 to 12 hours, depending on the particular product. Potential side effects include headache, drowsiness, and nervousness.

What Is Chlorpheniramine?

Chlorpheniramine is an antihistamine medication used as an active ingredient in many different non-prescription products (such as Chlor-Trimeton®) and prescription drugs (such as Tussionex®). It is used to treat allergies such as hay fever, hives, and the common cold.
 
(Click What Is Chlorpheniramine Used For? for more information, including possible off-label uses.)
 

Potential Side Effects

Just like any medicine, chlorpheniramine can cause side effects. However, not everyone who takes the drug will experience problems. Some people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
 
Common side effects of chlorpheniramine include but are not limited to:
 
  • Drowsiness
  • Headaches
  • Nervousness or excitability
  • Dry mouth.
     
(Click Chlorpheniramine Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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