Guaifenesin Dosage

A person's age can affect the dose of guaifenesin that should be taken, as can weight when giving the medication to children. In general, adults should not take more than 2400 mg in 24 hours; children ages 6 to 11 should not take more than 1200 mg in 24 hours. It is important to drink plenty of water during treatment with guaifenesin.

An Introduction to Dosing With Guaifenesin

The recommended dosage of guaifenesin (an active ingredient in Mucinex®, Robitussin®, and many other medications) will vary, depending on a number of factors, including:
  • The particular product
  • Your age
  • The medical condition being treated
  • How you respond to guaifenesin
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust this amount unless your healthcare provider specifically tells you to do so.

Guaifenesin Dosage for Adults

Most guaifenesin products are approved for use in adults and children age 12 and older. Depending on the particular product, a typical guaifenesin dose is 200 to 400 mg every 4 hours (not to exceed 2400 mg per day) for immediate-release products and 600 to 1200 mg every 12 hours (not to exceed 2400 mg in 24 hours) for extended-release products.
Keep in mind that these are general guidelines and specific medications may have different directions. Be sure to follow the directions for your particular product.

Guaifenesin Dosing for Children

In general, guaifenesin can be dosed by age or by weight for children. Based on weight, a standard recommended dosage is 0.35 mg per kg per day (0.16 mg per pound per day), divided into smaller doses given every four to six hours.
Based on age, dosing guidelines for immediate-release guaifenesin are as follows:
  • Age 4 to 5 years: 50 to 100 mg every 4 hours, not to exceed 600 mg in 24 hours
  • Age 6 to 11 years old: 100 to 100 mg every 4 hours, not to exceed 1200 mg in 24 hours.
Extended-release guaifenesin (Mucinex) is not approved for use in children under the age of 12.
Cold or cough medications (including guaifenesin) should not be used in children under four years old, unless your child's healthcare provider specifically recommends such products. Since the labels for cough and cold products do not currently list appropriate dosages for children under the age of four, be sure to ask your healthcare provider for the correct dosage for your particular child.
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Guaifenesin Medication Information

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