Guaifenesin Dosage

Guaifenesin Dosing for Children

In general, guaifenesin can be dosed by age or by weight for children. Based on weight, a standard recommended dosage is 0.35 mg per kg per day (0.16 mg per pound per day), divided into smaller doses given every four to six hours.
Based on age, dosing guidelines for immediate-release guaifenesin are as follows:
  • Age 4 to 5 years: 50 to 100 mg every 4 hours, not to exceed 600 mg in 24 hours
  • Age 6 to 11 years old: 100 to 100 mg every 4 hours, not to exceed 1200 mg in 24 hours.
Extended-release guaifenesin (Mucinex) is not approved for use in children under the age of 12.
Cold or cough medications (including guaifenesin) should not be used in children under four years old, unless your child's healthcare provider specifically recommends such products. Since the labels for cough and cold products do not currently list appropriate dosages for children under the age of four, be sure to ask your healthcare provider for the correct dosage for your particular child.

What Is the Dosage for Other Uses?

For any use other than to make coughs more productive, it is recommended that you consult your healthcare provider before taking guaifenesin.

General Information on Taking Guaifenesin

Considerations to keep in mind during treatment with guaifenesin include the following:
  • This medication comes in different forms, including tablets, long-acting tablets, capsules, and syrup. It is taken by mouth every 4 to 12 hours, depending on the particular product.
  • You can take a dose of guaifenesin with food or on an empty stomach. If the medication bothers your stomach, try taking it with a little food.
  • Because several different guaifenesin products are available, be sure to follow the instructions for your particular product.
  • Extended-release guaifenesin tablets (Mucinex) must be swallowed whole. Do not break or crush them.
  • Be sure to drink plenty of water or other fluids while taking guaifenesin.
  • For the medication to work properly, it must be taken as directed.
  • If you are unsure about anything related to your guaifenesin dosage, please talk with your doctor, nurse, or pharmacist.
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Guaifenesin Medication Information

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