Drug Interactions With Gemifloxacin

When certain medications are combined with gemifloxacin, there is a possibility for negative drug interactions. Some of these reactions can decrease the effectiveness of the medications or increase your risk for side effects. Certain antacids, corticosteroids, and the typhoid vaccine are among the substances that can react with gemifloxacin. You may need to separate your doses of these medications by several hours to avoid any complications.

An Overview of Gemifloxacin Interactions

Gemifloxacin mesylate (Factive®) is a prescription medication used to treat bacterial infections, including bronchitis and pneumonia. This medication may potentially react with several other medications.
 
Some of the drugs that may lead to interactions with gemifloxacin include but are not limited to:
 
  • Aluminum, calcium, or magnesium antacids (Alternagel®, Gaviscon®, Maalox®, Mylanta®, Tums®, and many others)
  • Corticosteroids, such as:
 
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Ovapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
 
 
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Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD
 
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