Drug Interactions With Gemifloxacin

Taking probenecid with gemifloxacin may increase the amount of gemifloxacin in your blood, increasing your risk for side effects. Be especially watchful for gemifloxacin side effects if you take these medications together.
Sevelamer can bind to gemifloxacin in the digestive tract, decreasing the amount that is absorbed into the bloodstream. Take these medications at different times of the day to avoid this interaction.
Sucralfate can bind to gemifloxacin in the digestive tract, decreasing the amount that is absorbed into the bloodstream. You should take your gemifloxacin dose at least two hours before or after your dose of sucralfate.
Typhoid Vaccine
Antibiotics, including gemifloxacin, may decrease the effectiveness of the typhoid vaccine. This interaction only occurs with the oral typhoid vaccine. It is generally recommended that the oral typhoid vaccine be postponed for at least a day after finishing gemifloxacin.
Vitamins or Supplements With Aluminum, Magnesium, Calcium, Zinc, or Iron
Aluminum, magnesium, zinc, calcium, and iron can bind to gemifloxacin in the digestive tract, reducing the amount of the medication that is absorbed into the bloodstream. Do not take vitamins or supplements that contain aluminum, magnesium, calcium, zinc, or iron within three hours before or two hours after a dose of gemifloxacin.
There have been reports that combining gemifloxacin with warfarin may increase the risk for bleeding. If you take these medications together, your healthcare provider may need to monitor you more closely.

Final Thoughts

It is possible that not all gemifloxacin drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.
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