Dextromethorphan Dosage

Dextromethorphan Dosage for Pseudobulbar Affect

The standard dosage of dextromethorphan for treating pseudobulbar affect (PBA), when used in combination with quinidine, is dextromethorphan 20 mg and quinidine 10 mg once a day for seven days. Starting on day eight, it is usually increased to dextromethorphan 20 mg and quinidine 10 mg twice a day, taken about 12 hours apart.

General Information on Taking Dextromethorphan

Some considerations to keep in mind during treatment with dextromethorphan include the following:
  • This medication comes in many different strengths and forms. It is usually taken every 4 to 12 hours, but the specific directions for each individual product can vary substantially. Make sure to refer to the directions for your specific dextromethorphan medication.
  • It generally does not matter if you take dextromethorphan with or without food. Try taking it with food if it seems to upset your stomach.
  • Do not use a household spoon to measure liquid dextromethorphan. Household spoons are not accurate enough, so you may get the wrong dose. Use the measuring spoon or dosage cup that came with the medicine, or ask your pharmacist for an appropriate measuring device.
  • If you are using the strips, allow them to dissolve on your tongue.
  • If you are using the lozenges, let them dissolve in your mouth. Do not swallow them whole.
  • For the medication to work properly, it must be taken as prescribed.
  • If you are unsure about anything related to dosing with dextromethorphan, please talk to your healthcare provider or pharmacist. Do not stop taking the drug without first discussing it with your healthcare provider. 
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Dextromethorphan Medication Information

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