Afrin Nasal Spray

Afrin® (oxymetazoline nasal spray) is an over-the-counter nasal spray used to temporarily relieve nasal congestion due to the common cold, allergies, or sinus infections or inflammation. Afrin nasal spray should not be used for more than three days in a row, due to the risk of worsening the congestion.
 
The active ingredient in Afrin is part of a group of drugs called decongestants. Specifically, it works by stimulating certain receptors known as alpha-adrenergic receptors. In the lining of the nasal passages, this action causes the blood vessels to constrict, allowing less fluid to leave the blood vessels and decreasing inflammation. This helps to relieve nasal congestion.
 
Although most people tolerate this nasal spray well, it is not suitable for everyone. Some of the common side effects include sneezing and temporary burning or stinging. Before using Afrin, make sure to talk to your healthcare provider about any other medical conditions you may have or any other medications you are taking (including vitamins and herbal supplements).
 
(Click Afrin for more information on how Afrin nasal spray works, its uses, potential side effects, and tips on when and how to effectively use this medication.)
 
Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD