Drug Interactions With Chlorpheniramine

Anticholinergic drugs, monoamine oxidase inhibitors, and pramlintide are some of the medications that may cause drug interactions with chlorpheniramine. These interactions could reduce the effectiveness of the medicines or lead to side effects such as drowsiness, dry eyes, or difficulty passing urine. In order to decrease your risk of interactions, tell your healthcare provider about all other medications you are taking.

Chlorpheniramine Interactions: An Overview

Chlorpheniramine (an active ingredient in Chlor-Trimeton®, Tussionex®, and many other medications) can potentially interact with a number of other medicines. Some of the medications that may lead to drug interactions with chlorpheniramine include but are not limited to:
 
  • Acetylcholinesterase inhibitor medications, such as:
 
 
  • Anticholinergic drugs, such as:
 
 
  • Monoamine oxidase inhibitors (MAOIs), such as:
 
 
  • Other products that cause drowsiness, such as:
 
 
  • Phenothiazine medications, such as:
 
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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