Chlorpheniramine Maleate Dosage

Chlorpheniramine maleate is an antihistamine medication used as an active ingredient in many different non-prescription medicines (such as Chlor-Trimeton®) and prescription drugs. It is used to treat allergies such as hay fever, hives, and the common cold. Chlorpheniramine maleate is one of the two most common forms of the medication (the other is chlorpheniramine tannate).
Depending on the particular product, a typical chlorpheniramine maleate dosage for adults is 4 mg every 4 to 6 hours for immediate-release products or 8 to 12 mg every 8 to 12 hours for various extended-release products.
In general, chlorpheniramine maleate dosing for children is determined by age or weight. Based on weight, a standard recommended dosage is 0.35 mg per kg per day (0.16 mg per pound per day), divided up into smaller doses given every four to six hours. Based on age, the recommended dose of chlorpheniramine is as follows:
  • Ages 2 to 6 -- 1 mg every 4 to 6 hours, not to exceed 6 mg in 24 hours
  • Ages 6 to 12 -- 2 mg every 4 to 6 hours, not to exceed 12 mg in 24 hours
  • Age 12 and older -- usual adult dosing.
(Click Chlorpheniramine Dosage for more detailed dosing guidelines for chlorpheniramine maleate, including tips and precautions for those using this antihistamine medication.)
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