Chlorpheniramine for the Common Cold

Chlorpheniramine is an antihistamine medication. It is available by itself in various non-prescription medications or in combination with other active ingredients in various prescription and non-prescription medications. The approved uses may vary, depending on the particular product. You may use chlorpheniramine for the common cold, allergies, or hives.
 
Chlorpheniramine is part of a class of drugs called antihistamines. Specifically, it is an H1 receptor antagonist. This means that it blocks a specific type of histamine receptor in the body known as H1 receptors. Chlorpheniramine also blocks acetylcholine receptors, an action that produces some of the unpleasant side effects of the medication, such as dry mouth or difficulty urinating, but also helps to relieve a runny nose.
 
Some chlorpheniramine products are approved for use in children, depending on the particular strength. Chlorpheniramine and similar medications should not be used to treat the common cold in children under four years old, as cold medications have not been shown to be effective or safe in young children.
 
(Click What Is Chlorpheniramine Used For? for more information about using chlorpheniramine for the common cold and to learn about possible off-label uses for the medicine.)
 
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