Afrin

Afrin is an over-the-counter medication used to relieve nasal congestion caused by the common cold, allergies, or sinus infections. This medication comes in the form of a nasal spray and is used in each nostril twice daily. It works by constricting the blood vessels in the nasal passages and decreasing inflammation. Potential side effects include sneezing and temporary burning or stinging.

What Is Afrin?

Afrin® (oxymetazoline nasal spray) is a non-prescription medication used to temporarily relieve nasal congestion due to the common cold, allergies, or sinus infections or inflammation. It should not be used for more than three days in a row, due to the risk making the congestion worse.
 
(Click Afrin Uses for more information, including possible off-label uses.)
 

Who Makes This Medication?

Afrin is manufactured by Schering-Plough HealthCare Products, Inc.
 

How Does It Work?

The active ingredient in Afrin is part of a group of drugs called decongestants. Specifically, it works by stimulating certain receptors known as alpha-adrenergic receptors. In the lining of the nasal passages, this action causes the blood vessels to constrict, allowing less fluid to leave the blood vessels and decreasing inflammation. This helps to relieve nasal congestion.
 

When and How to Take Afrin

Some general considerations for those using Afrin include the following:
 
  • This medication comes in the form of a nasal spray. It is sprayed into each nostril twice daily.
     
  • Afrin products come in a spray bottle or a pump mist bottle. Some people may prefer one over the other for various reasons.
     
  • The pump mist products should be shaken well before each use.
     
  • The pump mist products need to be primed by depressing the pump several times before the first use. The spray bottle products do not need to be primed.
     
  • Do not tip your head when using these products.
     
  • In order to prevent spreading infections, do not share Afrin nasal spray with other people.
     
  • For Afrin to work properly, it must be taken as directed.
     

Dosing Information

There is only one standard recommended dosage for this product. As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 
(Click Afrin Dosage for more information.)
 

Side Effects of Afrin

Just like any medicine, Afrin can cause side effects. However, not everyone who takes the drug will experience problems. Most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider. Serious side effects are less common.
 
Possible side effects of Afrin include but are not limited to:
 
  • Temporary burning or stinging
  • Sneezing
  • Worsening of congestion with prolonged use (see Afrin Addiction).
     
(Click Afrin Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 

Drug Interactions

Afrin may interact with some other medications (see Afrin Drug Interactions).
 

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Afrin if you have:
 
Also, let your healthcare provider know if you are:
 
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Afrin Warnings and Precautions to learn more, including information on who should not take the drug.)
 

What If I Take an Overdose?

An overdose with this medication could potentially cause serious problems. If you happen to overdose on this medication, seek immediate medical attention.
 
(Click Afrin Overdose for more information.)
 

How Should Afrin Be Stored?

Afrin should be stored at room temperature. Keep this and all other medications out of the reach of children.
 

What Should I Do If I Miss a Dose?

If you do not take your Afrin as scheduled, take your missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose.
 

Available Strengths

Several different Afrin products are available, although they all contain the same active ingredient (oxymetazoline 0.05%). These products include:
 
  • Afrin No Drip Original
  • Afrin No Drip Severe Congestion
  • Afrin No Drip Extra Moisturizing
  • Afrin No Drip Sinus
  • Afrin No Drip All Night.
     
While all of these products contain oxymetazoline in the same concentration, they differ in the other ingredients (such as menthol or camphor) that they may contain. All Afrin products, except Afrin No Drip All Night Pump Mist, are available in spray form or pump mist form.
 

Generic Afrin

This medication is available in generic form.
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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