The active ingredient in Afrin nose spray is part of a group of drugs called decongestants. Specifically, it works by stimulating certain receptors known as alpha-adrenergic receptors. In the lining of the nasal passages, this action causes the blood vessels to constrict, allowing less fluid to leave the blood vessels and decreasing inflammation. This helps to relieve nasal congestion.
Afrin nose spray is approved for use in adults and children who are at least six years old. Some possible
off-label uses include:
- Treating ear congestion due to an ear infection or other causes
- Treating nosebleeds
- Preventing ear discomfort during air travel.
(Click Afrin Uses for more information on Afrin nose spray, including how this medication works, its safety in children, and other uses.)